vitamin k1 is administered as an antidote for poisoning with

By 2019, all rodenticides manufactured by d-CON®, the most popular brand of rodenticides, will be made with cholecalciferol. Unfortunately, the first-generation anticoagulants are less effective as rodenticides, which has caused producers to transition to either bromethalin or cholecalciferol, neither of which have safe, accessible and inexpensive antidotes like the anticoagulants. warfarin), bromethalin (neurotoxin), or cholecalciferol (vitamin D3). This regulation has caused rodenticide manufacturers to change active ingredients to first-generation anticoagulants (i.e. In 2011, the Environmental Protection Agency (EPA) enacted regulations banning the use of second-generation anticoagulants in residential rodenticides. Though there was the potential for life-threatening hemorrhage within 72 hours of ingestion, an inexpensive antidote (vitamin K1) was available and effective if administered prior to clinical signs. Historically, second-generation anticoagulants were the most common active ingredient in rodenticides.

Ingestion of rodenticides by companion animals is consistently one of the most common intoxications in veterinary medicine.

Vitamin k1 is administered as an antidote for poisoning with